薬剤部の研究

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業績

 

2005年

Norihiro Kobayashi, Mamoru Ohtoyo, Eriko Wada, Yoshinori Kato, Nariyasu Mano and Junichi Goto:
Generation of a single-chain Fv fragment for the monitoring of deoxycholic acid residues anchored on endogenous proteins.
Steroids, 70, 285-294 (2005).
DOI: 10.1016/j.steroids.2004.11.012

Takaaki Goto,Akihiro Shibata, Daisuke Sasaki, Naoto Suzuki, Takanori Hishinuma,Genta Kakiyama, Takashi Iida, Nariyasu Mano and Junichi Goto:
Identification of a novel conjugate in human urine: Bile acid acyl galactosides.
Steroids, 70, 185-192 (2005).
DOI: 10.1016/j.steroids.2004.12.006

Genta Kakiyama, Shinji Sadakiyo, Takashi Iida, Kumiko Mushiake, Takaaki Goto, Nariyasu Mano, Junichi Goto and Toshio Nambara:
Chemical synthesis of 24-β-D-galactopyranosides of bile acids: a new type of bile acid conjugates in human urine.
Chem. Phys. Lipids, 134, 141-150 (2005).
DOI: 10.1016/j.chemphyslip.2005.01.002

Takeji Takamura-Enya, Nariyasu Mano, Nobuo Kawahara, Junichi Goto and Keiji Wakabayashi:
Formation of DNA adducts with cholyl adenylate, a putative intermediate for biosynthesis of cholyl-CoA.
Chem. Res. Toxicol., 18, 1715-1720 (2005).
DOI: 10.1021/tx050159

Muneo Numasaki, Mika Watanabe, Takashi Suzuki, Hidenori Takahashi, Akira Nakamura, Florencia McAllister, Takanori Hishinuma, Junichi Goto, Michael T. Lotze, Jay K. Kolls and Hidetada Sasaki:
IL-17 enhances the net Angiogenic activity and in vivo growth of human non-small cell lung cancer in ACID mice through promoting CXCR-2-dependent angiogenesis.
J. Immunol., 175, 6177-6189 (2005).

Norihiro Kobayashi, Tsuyoshi Karibe and Junichi Goto:
Dissociation-independent selection of high affinity phage antibodies against haptens using cleavable biotin-conjugated haptenic derivatives.
Anal. Biochem., 347, 287-296 (2005).

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