薬剤部の研究

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業績

 

2017年

Hidaka H, Ozawa D, Kuriyama S, Obara T, Nakano T, Kakuta R, Nomura K, Watanabe K, Katori Y.
Risk factors for delayed oral dietary intake in patients with deep neck infections including descending necrotizing mediastinitis.
European archives of oto-rhino-laryngology, 274(11), 3951-3958 (2017).
DOI: 10.1007/s00405-017-4716-3

Ishikuro M, Matsubara H, Kikuya M, Obara T, Sato Y, Metoki H, Isojima T, Yokoya S, Kato N, Tanaka T, Chida S, Ono A, Hosoya M, Yokomichi H, Yamagata Z, Tanaka S, Kure S, Kuriyama S.
Disease prevalence among nursery school children after the Great East Japan earthquake.
BMJ Glob Health,2(2), e000127 (2017).
DOI: 10.1136/bmjgh-2016-000127

Kikuya M, Matsubara H, Ishikuro M, Sato Y, Obara T, Metoki H, Isojima T, Yokoya S, Kato N, Tanaka T, Chida S, Ono A, Hosoya M, Yokomichi H, Yamagata Z, Tanaka S, Kure S, Kuriyama S.
Alterations in physique among young children after the Great East Japan Earthquake: Results from a nationwide survey.
Journal of Epidemiology, 27(10), 462-468 (2017).
DOI: 10.1016/j.je.2016.09.012

Nishigori H, Nishigori T, Sakurai K, Mizuno S, Obara T, Metoki H, Watanabe Z, Iwama N, Ishikuro M, Tatsuta N, Nishijima I, Sugawara J, Kuriyama S, Fujiwara I, Arima T, Nakai K, Takahashi F, Yaegashi N; Japan Environment & Children’s Study Group.
Pregnant Women's Awareness of Social Capital in the Great East Japan Earthquake-Affected Areas of Miyagi Prefecture: The Japan Environment and Children's Study. Disaster medicine and public health preparedness,11(3), 355-364 (2017).
DOI: 10.1017/dmp.2016.150

Nishigori H, Obara T, Nishigori T, Mizuno S, Metoki H, Hoshiai T, Watanabe Z, Sakurai K, Ishikuro M, Tatsuta N, Nishijima I, Fujiwara I, Kuriyama S, Arima T, Nakai K, Yaegashi N; Japan Environment & Children's Study Group.
Selective serotonin reuptake inhibitors and risk of major congenital anomalies for pregnancies in Japan: A nationwide birth cohort study of the Japan Environment and Children's Study.
Congenital anomalies, 57(3), 72-78 (2017).
DOI: 10.1111/cga.12202

Mami Ishikuro, Sergio Ramón Gutiérrez Ubeda, Taku Obara, Toshihide Saga, Naofumi Tanaka, Chiyo Oikawa, Keisei Fujimori.
Exploring risk factors of patient falls: A retrospective hospital record study in Japan.
Tohoku J. Exp. Med., 243(3), 195-203 (2017).

Miki Hosaka, Ryusuke Inoue, Michihiro Satoh, Daisuke Watabe, Tomohiro Hanazawa, Takayoshi Ohkubo, Kei Asayama, Taku Obara, and Yutaka Imai on behalf of The J-HOME-ALB Study group.
Effect of amlodipine, efonidipine, and trichlormethiazide on home blood pressure and upper-normal microalbuminuria assessed by casual spot urine test in essential hypertensive patients.
Clin. Exp. Hypertens., 1-8 (2017).

Yuko Igarashi, Taku Obara, Mami Ishikuro, Hiroko Matsubara, Michiko Shigihara, Hirohito Metoki, Masahiro Kikuya, Yoichi Sameshima, Hirofumi Tachibana, Mari Maeda-Yamamoto and Shinichi Kuriyama.
Randomized controlled trial of the effects of consumption of ‘Yabukita’ or ‘Benifuuki’ encapsulated tea-powder on low-density lipoprotein cholesterol level and body weight.
Food Nutr. Res., 61(1), 1654-1661 (2017).
DOI: 10.1080/16546628.2017.1334484

Takahiro Suga, Miki Shimada, Masamitsu Maekawa, Hiroyuki Suzuki, Masaru Mori, Tatsuma Okazaki, Akira Inoue, Hiroaki Yamaguchi and Nariyasu Mano.
A rapid and simple UHPLC-UV method for quantitative determination of erlotinib and its active metabolites OSI-420 in human serum, and its application in a non-small cell lung cancer patient.
Chromatography, 38, 95-100 (2017).
DOI: 10.15583/jpchrom.2017.007

Eiji Hishinuma, Fumika Akai, Yoko Narita, Masamitsu Maekawa, Hiroaki Yamaguchi, Nariyasu Mano, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka.
Functional characterization of 21 allelic variants of dihydropyrimidinase.
Biochem. Pharmacol., 143, 118-128 (2017).
DOI: 10.1016/j.bcp.2017.06.121

Tatsuya Higashi, Shui Watanabe, Koki Tomaru, Wataru Yamazaki, Kazumi Yoshizawa, Shojiro Ogawa, Hidenori Nagao, Kouichi Minato, Masamitsu Maekawa and Nariyasu Mano.
Unconjugated bile acids in rat brain: Analytical method based on LC/ESI-MS/MS with chemical derivatization and estimation of their origin by comparison to serum levels.
Steroids, 125, 107-113 (2017).
DOI: 10.1016/j.steroids.2017.07.001

Hiromasa Iboshi, Hiroaki Yamaguchi, Hiroyuki Suzuki, Masafumi Kikuchi, Masaki Tanaka, Shinya Takasaki, Akiko Takahashi, Masamitsu Maekawa, Miki Shimada, Yoshinori Okada and Nariyasu Mano.
Development of a liquid chromatography-tandem mass spectrometric method for quantification of mycophenolic acid and its glucuronides in dried blood spot samples.
Ther. Drug Monit., 39, 648-653 (2017).
DOI: 10.1097/FTD.0000000000000458

Tetsuro Matsuhashi, Takeya Sato, Shin-ichiro Kanno, Takehiro Suzuki, Akihiro Matsuo, Yuki Oba, Motoi Kikusato, Emi Ogasawara, Tai Kudo, Kosuke Suzuki, Osamu Ohara, Hiroko Shimbo, Fumika Nanto, Hiroaki Yamaguchi, Daisuke Saigusa, Yasuno Mukaiyama, Akiko Watabe, Koichi Kikuchi, Hisato Shima, Eikan Mishima, Yasutoshi Akiyama, Yoshitsugu Oikawa, HO Hsin-Jung, Yukako Akiyama, Chitose Suzuki, Mitsugu Uematsu, Masaki Ogata, Naonori Kumagai, Masaaki Toyomizu, Atsushi Hozawa, Nariyasu Mano, Yuji Owada, Setsuya Aiba, Teruyuki Yanagisawa, Yoshihisa Tomioka, Shigeo Kure, Sadayoshi Ito, Kazuto Nakada, Ken-ichiro Hayashi, Hitoshi Osaka, and Takaaki Abe.
Mitochonic acid 5 (MA-5) facilitates ATP synthase oligomerization and cell survival in various mitochondrial diseases.
EBioMedicine, 20, 27-38 (2017).
DOI: 10.1016/j.ebiom.2017.05.016

Toshihiro Sato, Eikan Mishima, Nariyasu Mano, Takaaki Abe and Hiroaki Yamaguchi.
Potential drug interactions mediated by renal organic anion transporter OATP4C1.
J. Pharmacol. Exp. Ther.,362, 271-277 (2017)
DOI: 10.1124/jpet.117.241703.

Yoichiro Asai, Tetsuya Yamada, Sohei Tsukita, Kei Takahashi, Masamitsu Maekawa, Midori Homma, Masanori Ikeda, Keigo Murakami, Yuichiro Munakata, Yuta Shirai, Sshinjiro Kodama, Takashi Sugisawa, Yumiko Chiba, Yasuteru Kondo, Keizo Kaneko, Kenji Uno, Shojiro Sawada, Junta Imai, Yasuhiro Nakamura, Hiroaki Yamaguchi, Kozo Tanaka, Hironobu Sasano, Nariyasu Mano, Yoshiyuki Ueno, Tooru Shimosegawa and Hideki Katagiri:
Activation of the Hypoxia Inducible Factor 1 Alpha Subunit Pathway in Steatotic Liver Contributes to Formation of Cholesterol Gallstones.
Gastroenterology, 152, 1521-1535 (2017).
DOI: 10.1053/j.gastro.2017.01.001

Hiroki Hosono, Masaki Kumondai, Masamitsu Maekawa, Hiroaki Yamaguchi, Nariyasu Mano, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka:
Functional characterization of 34 CYP2A6 allelic variants by assessment of nicotine C-oxidation and coumarin 7-hydroxylation activities.
Drug Metab. Dispos., 45(5), 279-285(2017).
DOI: 10.1124/dmd.116.073494

Hideaki Ishii, Hiroaki Yamaguchi and Nariyasu Mano:
Expanding the versatility of a quantitative determination range adjustment technique using in-source CID in LC/MS/MS.
Chromatography, 38, 59-63 (2017).
DOI: 10.15583/jpchrom.2017.004

Kazuki Abe, Hiroyuki Suzuki, Masamitsu Maekawa, Miki Shimada, Hiroaki Yamaguchi and Nariyasu Mano:
Matrix effect–corrected liquid chromatography/tandem mass-spectrometric method for determiningacylcarnitines in human urine.
Clin. Chim. Acta, 468,187-194 (2017).
DOI: 10.1016/j.cca.2017.03.001.

Hidekazu Nishigori, Taku Obara, Toshie Nishigori, Hirohito Metoki, Mami Ishikuro, Satoshi Mizuno, Kasumi Sakurai, Nozomi Tatsuta, Ichiko Nishijima, Ikuma Fujiwara, Takahiro Arima, Kunihiko Nakai, Nariyasu Mano, Shinichi Kuriyama, Nobuo Yaegashi and Japan Environment & Children’s Study Group :
Drug Use before and during Pregnancy in Japan: The Japan Environment and Children’s Study.
Pharmacy, 5(2),(2017).
DOI:10.3390/pharmacy5020021

Takahiro Suga, Hiroaki Yamaguchi, Toshihiro Sato, Masamitsu Maekawa, Junichi Goto, Nariyasu Mano:
Preference of conjugated bile acids over unconjugated bile acids as substrates for OATP1B1 and OATP1B3.
PLOS ONE, 12(1), e0169719 (2017).
DOI: 10.1371/journal.pone.0169719

Shinya Takasaki, Masafumi Kikuchi, Yoshihide Kawasaki, Akihiro Ito, Yoichi Arai, Hiroaki Yamaguchi and Nariyasu Mano:
Severe toxicity induced by accumulation of active sunitinib metabolite in a Japanese patient with renal cell carcinoma: a case report.
J. Med. Case. Rep., 11(28), (2017).
 DOI: 10.1186/s13256-016-1185-z.

Taku Obara, Hidekazu Nishigori, Toshie Nishigori, Hirohito Metoki, Mami Ishikuro, Nozomi Tatsuta, Satoshi Mizuno, Kasumi Sakurai, Ichiko Nishijima, Yuriko Murai, Ikuma Fujiwara, Takahiro Arima, Kunihiko Nakai, Nariyasu Mano, Nobuo Yaegashi, Shinichi Kuriyama & on behalf of the JECS group:
Prevalence and determinants of inadequate use of folic acid supplementation in Japanese pregnant women: the Japan Environment and Children’s Study (JECS).
J. Matern. Fetal. Neonatal. Med., 30(5), 588-593(2017).
DOI: 10.1080/14767058.2016.1179273.

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