薬剤部の研究

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業績

 

2014年

Masamitsu Maekawa, Miki Shimada, Takashi Iida, Junichi Goto, Nariyasu Mano:
Tandem mass spectrometric characterization of bile acids and steroid conjugates based on low-energy collision-induced dissociation.
Steroids, 80(1), 80-91 (2014).
DOI: http://dx.doi.org/10.1016/j.steroids.2013.11.016

Michihiro Satoh, Miki Hosaka, Kei Asayama, Masahiro Kikuya, Ryusuke Inoue, Hirohito Metoki, Megumi. Tsubota Utsugi, Azusa Hara, Takuo Hirose, Taku Obara, Takefumi Mori, Kazuhito Totsune, Haruhisa Hoshi, Nariyasu Mano, Yutaka Imai, Takayoshi Ohkubo:
Aldosterone-to-Renin Ratio and Nocturnal Blood Pressure Decline Assessed by Self-measurement of Blood Pressure at Home: The Ohasama Study.
Clin Exp Hypertens, 36(2), 108-14 (2014).
DOI: 10.3109/10641963.2014.892121

Noha Elnagar, Michihiro Satoh, Miki Hosaka, Kei Asayama, Kazuki Ishikura, Taku Obara, Nariyasu Mano, Takayoshi Ohkubo, Yutaka Imai:
The velocity of home blood pressure reduction in response to low-dose eplerenone combined with other antihypertensive drugs determined by exponential decay function analysis.
Clin Exp Hypertens, 36(2), 83-91 (2014).
DOI: 10.3109/10641963.2014.892117

Miki Shimada, Hoshimi Okawa, Takahiro Maejima, Toshiki Yanagi, Kanehiko Hisamichi, Masaki Matsuura, Kazutoshi Akasaka, Masami Tsuchiya, Yasuteru Kondo, Tooru Shimosegawa, Masaru Mori, Masamitsu Maekawa, Hiroyuki Suzuki, and Nariyasu Mano:
A quantitative HPLC-UV method for determination of serum sorafenib and sorafenib N-oxide and its application in hepatocarcinoma patients.
Tohoku J Exp Med., 233(2), 103-112 (2014).
DOI: 10.1620/tjem.233.103

Masamitsu Takahashi, Takahiro Saito, Miyabi Ito, Chiharu Tsukada, Yuki Katono, Hiroki Hosono, Masamitsu Maekawa, Miki Shimada, Nariyasu Mano, Akifumi Oda, Noriyasu Hirasawa, Masahiro Hiratsuka:
Functional characterization of twenty-one CYP2C19 allelic variants for clopidogrel 2-oxidation.
Pharmacogenomics J, (8 July 2014).

Hirohito Metoki, Taku Obara, Kei Asayama, Michihiro Satoh, Miki Hosaka, Noha Elnagar, Yoshinori Miyawaki, Iwao Kojima, Takayoshi Ohkubo, Yutaka Imai; for the Japan-Home versus Office Blood Pressure Measurement Evaluation – Augmentation Index Study Investigators:
Differential effects of angiotensin II receptor blocker and losartan/hydrochlorothiazide combination on central blood pressure and augmentation index.
Clin Exp Hypertens., 1-9(1 Oct 2014). [Epub ahead of print]

Nobuaki Tanaka, Hiroaki Yamaguchi and Nariyasu Mano:
Transport of eicosapentaenoic acid-derived PGE3, PGF3α, and TXB3 by ABCC4.
PLOS ONE, 9(10), e109270 (2014).
DOI: 10.1371/journal.pone.0109270

Hiroaki Yamaguchi, Kazuaki Miyamori, Toshihiro Sato, Jiro Ogura, Masaki Kobayashi, Takehiro Yamada, Nariyasu Mano and Ken Iseki:
Quantification of intracellular and extracellular digoxin and ouabain by liquid chromatography/electrospray ionization tandem mass spectrometry.
J Chromatog B, 972, 73-80 (2014).
DOI: http://dx.doi.org/10.1016/j/jchromb.2014.09.043

Mohammadali Khan Mirzaei, Harald Eriksson, Kie Kasuga, Elisabeth Haggård-Lkungquist, Anders S Nilsson:
Genomic, Proteomic, Morphological, and Phylogenetic Analyses of vB_EcoP_Su10, a podoviridae Phage with C3 Morphology.
PLOS ONE, 9(12), e116294 (2014).

Toshihiro Sato, Hiroaki Yamaguchi, Takuma Kogawa, Takaaki Abe, Nariyasu Mano:
Organic anion transporting polypeptides 1B1 and 1B3 play an important role in uremic toxin handling and drug-uremic toxin interactions in the liver.
JPPS, 17(4), 475-484 (2014).

Nobuaki Tanaka, Hiroaki Yamaguchi, Ayako Furugen, Jiro Ogura, Masaki Kobayashi, Takehiro Yamada, Nariyasu Mano, Ken Iseki:
Quantification of intracellular and extracellular eicosapentaenoic acid-derived 3-series prostanoids by liquid chromatography/electrospray ionization tandem mass spectrometry.
Prostaglandins Leukot Essent Fatty Acids, 91(3), 61-71 (2014).
DOI: http://dx.doi.org/10.1016/j.plefa.2014.04.005

Michihiro Satoh, Akihiro Matsumoto, Azusa Hara, Saki Iwamori, Taku Obara, Masahiro Kikuya, Hirohito Metoki, Miki Hosaka, Kei Asayama, Nobuyuki Takahashi, Hiroshi Sato, Nariyasu Mano, Yutaka Imai, Takayoshi Ohkubo:
A Survey of Self-medication Practices and Related Factors in the General Population: the Ohasama Study.
Yakugaku Zasshi, 134(12), 1347-1355 (2014).

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