薬剤部の研究

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業績

 

2018年

Imai Y, Asayama K, Fujiwara S, Saito K, Sato H, Haga T, Satoh M, Murakami T, Metoki H, Kikuya M, Obara T, Inoue R, Ohkubo T.
Development and evaluation of a home nocturnal blood pressure monitoring system using a wrist-cuff device.
Blood Pressure Monitoring, 23(6), 318-326 (2018).
DOI: 10.1097/MBP.0000000000000351

Ishikuro M, Obara T, Osanai T, Yamanaka C, Sato Y, Mizuno S, Miyashita M, Kikuya M, Sakurai K, Hozawa A, Tomita H, Taki Y, Nagami F, Metoki H, Kuriyama S.
Strategic Methods for Recruiting Grandparents: The Tohoku Medical Megabank Birth and
Three-Generation Cohort Study.
The Tohoku Journal of Experimental Medicine, 246(2), 97-105 (2018).
DOI: 10.1620/tjem.246.97

Obara T, Ishikuro M, Tamiya G, Ueki M, Yamanaka C, Mizuno S, Kikuya M, Metoki H, Matsubara H, Nagai M, Kobayashi T, Kamiyama M, Watanabe M, Kakuta K, Ouchi M, Kurihara A, Fukuchi N, Yasuhara A, Inagaki M, Kaga M, Kure S, Kuriyama S.
Potential identification of vitamin B6 responsiveness in autism spectrum disorder utilizing phenotype variables and machine learning methods.
Scientific Report, 8(1), 14840 (2018).
DOI: 10.1038/s41598-018-33110-w

Ishikawa T, Obara T, Nishigori H, Miyakoda K, Ishikuro M, Metoki H, Ohkubo T, Sugawara J, Yaegashi N, Akazawa M, Kuriyama S, Mano N.
Antihypertensives prescribed for pregnant women in Japan: Prevalence and timing determined from a database of health insurance claims.
Pharmacoepidemiology and Drug Safety, 27(12), 1325-1334 (2018).
DOI: 10.1002/pds.4654

Nishigori H, Obara T, Nishigori T, Ishikuro M, Sakurai K, Hoshiai T, Saito M, Fujiwara I, Arima T, Nakai K, Kuriyama S, Mano N, Metoki H, Yaegashi N; Japan Environment & Children's Study Group.
Preconception folic acid supplementation use and the occurrence of neural tube defects in Japan: A nationwide birth cohort study of the Japan Environment and Children's Study.
Congenital anomalies, in press.
DOI: 10.1111/cga.12293

Satoh M, Murakami T, Asayama K, Hirose T, Kikuya M, Inoue R, Tsubota-Utsugi M, Murakami K, Matsuda A, Hara A, Obara T, Kawasaki R, Nomura K, Metoki H, Node K, Imai Y, Ohkubo T.
N-Terminal Pro-B-Type Natriuretic Peptide Is Not a Significant Predictor of Stroke Incidence After 5 Years - The Ohasama Study.
Circulation Journal, 82(8), 2055-2062 (2018).
DOI: 10.1253/circj.CJ-17-1227

Watabe D, Asayama K, Hanazawa T, Hosaka M, Satoh M, Yasui D, Obara T, Inoue R, Metoki H, Kikuya M, Imai Y, Ohkubo T; Hypertension Objective Treatment Based on Measurement by Electrical Devices of Blood Pressure (HOMED-BP) investigators.
Predictive power of home blood pressure indices at baseline and during follow-up in hypertensive patients: HOMED-BP study.
Hypertension Research, 41(8), 622-628 (2018).
DOI: 10.1038/s41440-018-0050-4

Hanazawa T, Asayama K, Watabe D, Tanabe A, Satoh M, Inoue R, Hara A, Obara T, Kikuya M, Nomura K, Metoki H, Imai Y, Ohkubo T; HOMED‐BP (Hypertension Objective Treatment Based on Measurement by Electrical Devices of Blood Pressure) Investigators.
Association Between Amplitude of Seasonal Variation in Self-Measured Home Blood Pressure and Cardiovascular Outcomes: HOMED-BP (Hypertension Objective Treatment Based on Measurement By
Electrical Devices of Blood Pressure) Study.
Journal of the American Heart Association, 7(10), e008509 (2018).
DOI: 10.1161/JAHA.117.008509

Kuniyoshi Y, Kikuya M, Miyashita M, Yamanaka C, Ishikuro M, Obara T, Metoki H, Nakaya N, Nagami F, Tomita H, Hozawa A, Tsuji I, Kure S, Yaegashi N, Yamamoto M, Kuriyama S.
Severity of eczema and mental health problems in Japanese schoolchildren: The ToMMo Child Health Study.
Allergology international, 67(4), 481-486 (2018).
DOI: 10.1016/j.alit.2018.02.009

Ohseto H, Ishikuro M, Kikuya M, Obara T, Igarashi Y, Takahashi S, Kikuchi D, Shigihara M, Yamanaka C, Miyashita M, Mizuno S, Nagai M, Matsubara H, Sato Y, Metoki H, Tachibana H, Maeda-Yamamoto M, Kuriyama S.
Relationships among personality traits, metabolic syndrome, and metabolic syndrome scores: The Kakegawa cohort study.
Journal of psychosomatic research, 107, 20-25 (2018).
DOI: 10.1016/j.jpsychores.2018.01.013

Satoh M, Asayama K, Kikuya M, Inoue R, Tsubota-Utsugi M, Obara T, Murakami K, Matsuda A, Murakami T, Nomura K, Metoki H, Imai Y, Ohkubo T.
Nocturnal blood pressure decline based on different time intervals and long-term cardiovascular risk: the Ohasama Study.
Clinical and Experimental Hypertension, 40(1), 1-7 (2018).
DOI: 10.1080/10641963.2016.1259324

Ogata S, Kamide K, Asayama K, Tabara Y, Kawaguchi T, Satoh M, Katsuya T, Sugimoto K, Hirose T, Inoue R, Hara A, Obara T, Kikuya M, Metoki H, Matsuda F, Staessen JA, Ohkubo T, Rakugi H, Imai Y.
Genome-wide association study for white coat effect in Japanese middle-aged to elderly people: The HOMED-BP study.
Clinical and Experimental Hypertension, 40(4), 363-369 (2018).
DOI: 10.1080/10641963.2017.1384481

Takashi Watanabe, Takahiro Saito, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Masaki Kumondai, Masamitsu Maekawa, Akifumi Oda, Daisuke Saigusa, Sakae Saito, Jun Yasuda, Masao Nagasaki, Naoko Minegishi, Masayuki Yamamoto, Hiroaki Yamaguchi, Nariyasu Mano, Noriyasu Hirasawa, Masahiro Hiratsuka.
Functional characterization of 40 CYP2B6 allelic variants by assessing efavirenz 8-hydroxylation.
Biochemical Pharmacology, 156, 420-430 (2018).
DOI: 10.1016/j.bcp.2018.09.010

Tomoya Kawazoe, Toshiyuki Yamamoto, Aya Narita, Kousaku Ohno, Kaori Adachi, Eiji Nanba, Atsuko Noguchi, Tsutomu Takahashi, Masamitsu Maekawa, Yoshikatsu Eto, Masafumi Ogawa, Miho Murata, and Yuji Takahashi.
Phenotypic variability of Niemann-Pick disease type C including a case with clinically pure schizophrenia: a case report.
BMC Neurology, 18(1), 117-122 (2018).
DOI: 10.1186/s12883-018-1124-2.

Akihiro Kanaya, Toshihiro Sato, Nobuo Fuse, Hiroaki Yamaguchi, Nariyasu Mano, and Masanori Yamauchi.
Impact of clinical factors and UGT1A9 and CYP2B6 genotype on inter-individual differences in propofol pharmacokinetics.
J. Anesth., 32(2), 236-243 (2018).
DOI: 10.1007/s00540-018-2470-3

Asuka Mogi, Ryo Yomoda, Syunya Kimura, Chisato Tsushima, Jun Takouda, Miho Sawauchi, Tomoko Maekawa, Hidenobu Ohta, Satoshi Nishino, Masataka Kurita, Nariyasu Mano, Noriko Osumi, and Takahiro Moriya.
Entrainment of the circadian clock in neural stem cells by epidermal growth factor is closely associated with ERK1/2-mediated induction of multiple clock-related genes.
Neuroscience, 379, 45-66(2018).
DOI: 10.1016/j.neuroscience.2018.02.045

Masayuki Kanamori, Masamitsu Maekawa, Ichiyo Shibahara, Ryuta Saito, Masashi Chonan, Miki Shimada, Yukihiko Sonoda, Toshihiro Kumabe, Mika Watanabe, Nariyasu Mano, and Teiji Tominaga.
Rapid detection of mutation in isocitrate dehydrogenase 1 and 2 gene using mass spectrometry.
Brain Tumor Pathology, 35(2), 90-96 (2018).
DOI: 10.1007/s10014-018-0317-0

Tomofumi Ishikawa, Taku Obara, Hidekazu Nishigori, Keiko Miyakoda, Ryusuke Inoue, Tetsuo Hoshiai, Masatoshi Saito, Nobuo Yaegashi, and Nariyasu Mano.
Development of algorithms to determine onset and delivery date of pregnancy using healthcare administrative data in a University Hospital in Japan.
Pharmacoepidemiol. Drug. Saf., 27, 751-762 (2018).
DOI: 10.1002/pds.4444

Eiji Hishinuma, Yoko Narita, Sakae Saito, Masamitsu Maekawa, Fumika Akai, Yuya Nakanichi, Jun Yasuda, Masao Nagasaki, Masayuki Yamamoto, Hiroaki Yamaguchi, Nariyasu Mano, Noriyasu Hirasawa, and Masahiro Hiratsuka.
Funstional characterization of 21 allelic variants of dihydropyrimidine dehydrogenase in 1,070 Japanese individuals.
Drug Metab. Dispos., 46, 1083-1090 (2018).
DOI: 10.1124/dmd.118.081737

Shinya Takasaki, Yoshihide Kawasaki, Masafumi Kikuchi, Masaki Tanaka, Masato Suzuka, Aoi Noda, Yuji Sato, Shinichi Yamashita, Koji Mitsuzuka, Hideo Saito, Akihiro Ito, Hiroaki Yamaguchi, Yoichi Arai, and Nariyasu Mano.
Relationships between sunitinib plasma concentration and clinical outcomes in Japanese patients with metastatic renal cell carcinoma.
Int. J. Clin. Oncol., 23, 936-943 (2018).
DOI: 10.1007/s10147-018-1302-7

Tomofumi Ishikawa, Taku Obara, Hidekazu Nishigori, Toshie Nishigori, Hirohito Metoki, Mami Ishikuro, Nozomi Tatsuta, Satoshi Mizuno, Kasumi Sakurai, Ichiko Nishijima, Yuriko Murai, Ikuma Fujiwara, Takahiro Arima, Kunihiko Nakai, Nobuo Yaegashi, Shinichi Kuriyama, Nariyasu Mano on behalf of the JECS Group.
Update on the prevalence and determinants of inadequate folic acid use in Japan evaluated with 91,538 pregnant women: The Japan Environment and Children’s Study.
J. Maternal-Fetal & Neonatal Medicine,19, 1-10 (2018).
DOI: 10.1080/14767058.2018.1494712

Yoshitomi Kanemitsu, Hiroki Tsukamoto, Yotaro Matsumoto, Kanako Nozawa-Kumada, Yoshinori Kondo, Takaaki Abe and Yoshihisa Tomioka.
Generation and characterization of anti-phenyl sulfate monoclonal antibodies and a potential use for phenyl sulfate analysis in human blood.
Biol. Pharm. Bull., 41(8), (2018).

Hiroki Tsukamoto, Shino Takeuchi, Kanae Kubota, Yohei Kobayashi, Sao Kozakai, Ippo Ukai, Ayumi Shichiku, Misaki Okubo, Muneo Numasaki, Yoshitomi Kanemitsu, Yotaro Matsumoto, Tomonori Nochi, Kouichi Watanabe, Hisashi Aso, and Yoshihisa Tomioka.
Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKKϵ-IRF3 axis activation.
J. Biol. Chem.,293(26):10186-10201 (2018).
DOI: 10.1074/jbc.M117.796631

Ryuichi Mashima, Masamitsu Maekawa, Aya Narita, Torayuki Okuyama, and Nariyasu Mano.
Elevation of plasma lysosphingomyelin-509 and urinary bile acid metabolite in Niemann-Pick disease type C-affected individuals.
Mol. Genet. Metab. Rep., 15, 90-95 (2018).
DOI: 10.1016/j.ymgmr.2018.03.005

Masaki Kumondai, Hiroki Hosono, Masamitsu Maekawa, Hiroaki Yamaguchi, Nariyasu Mano , Akifumi Oda, Noriyasu Hirasawa, Masahiro Hiratsuka.
Functional characterization of 9 CYP2A13 allelic variants by assessment of nicotine C-oxidation and coumarin 7-hydroxylation.
Mol. Genet. Metab. Rep., 33(1), 82-89 (2018).

Masafumi Kikuchi, Masaki Tanaka, Shinya Takasaki, Akiko Takahashi, Miki Akiba, Yasushi Matsuda, Masafumi Noda, Kanehiko Hisamichi, Hiroaki Yamaguchi, Yoshinori Okada and Nariyasu Mano.
Comparison of PETINIA and LC-MS/MS for determining plasma mycophenolic acid
concentrations in Japanese lung transplant recipients.
J. Pharm. Health Care Sci., 4, 7 (2018).
DOI: 10.1186/s40780-018-0101-7

Nobuhiro Ooba, Daisuke Tsutsumi, Naoko Kobayashi, Shinji Hidaka, Hiroyuki Hayashi, Taku Obara, Michihiro Satoh, Kiyoshi Kubota, Noriyasu Fukuoka.
Prevalence of Therapeutic Drug Monitoring for Lithium and the Impact of Regulatory Warnings: Analysis Using Japanese Claims Database.
Ther. Drug. Monit., 40(2), 252-256 (2018).
DOI: 10.1097/FTD.0000000000000483

Masaki Kumondai, Hiroki Hosono, Masamitsu Maekawa, Hiroaki Yamaguchi, Nariyasu Mano, Akifumi Oda, Noriyasu Hirasawa, and Masahiro Hiratsuka.
Funcitonal characterization of 9 CYP2A13 allelic variants by assessment of nicotine C-oxidation and coumarin 7-hydroxylation.
Drug Metabol. Pharmacokinet., 33(1), 82-89 (2018).
DOI: 10.1016/j.dmpk.2017.11.004

Shinya Takasaki, Masaki Tanaka, Masafumi Kikuchi, Masamitsu Maekawa, Yoshihide Kawasaki, Akihiro Ito, Yoichi Arai, Hiroaki Yamaguchi, and Nariyasu Mano.
Simultaneous analysis of oral anticancer drugs for renal cell carcinoma in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry.
Biomed. Chromatogr., 32, e4184 (2018).
DOI: 10.1002/bmc.4184

Masamitsu Maekawa, Masaru Mori, Masachika Fujiyoshi, Hisaki Suzuki, Kazunari Yanai, Aoi Noda, Masaki Tanaka, Shinya Takasaki, Masafumi Kikuchi, Kazutoshi Akasaka, Shigeki Kisara, Masaki Matsuura, Kanehiko Hisamichi, Mayumi Sato, Junichi Goto, Miki Shimada, Hiroaki Yamaguchi, and Nariyasu Mano.
A direct injection LC/ESI-MS/MS analysis of urinary cyclophosphamide as an anticancer drug for monitoring occupational exposure.
Chromatography, 39, 41-47 (2018).
DOI: 10.15583/jpchrom.2017.023

Toshihiro Sato, Hajime Ito, Ayaka Hirata, Takaaki Abe, Nariyasu Mano and Hiroaki Yamaguchi.
Interactions of crizotinib and gefitinib with organic anion-transporting polypeptides (OATP)1B1, OATP1B3, and OATP2B1: gefitinib shows contradictory interaction with OATP1B3.
Xenobiotica, 48(1), 73-78 (2018).
DOI: 10.1080/00498254.2016.1275880

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