薬剤部の研究

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業績

 

2011年

Taku Obara, Sentaro Oide, Takayoshi Ohkubo, Nariyasu Mano, and Yutaka Imai:
Role of pharmacists in the management of hypertensive patients.
Am. J. Hypertens., 24 (1), 2-3 (2011).
DOI: 10.1038/ajh.2010.208

Rieko Hatanaka, Taku Obara, Daisuke Watabe, Tomofumi Ishikawa, Takeo Kondo, Kazuki Ishikura, Tomoyuki Aikawa, Yoko Aono, Azusa Hara, Hirohito Metoki, Kei Asayama, Masahiro Kikuya, Nariyasu Mano, Takayoshi Ohkubo, Shin-Ichi Izumi, and Yutaka Imai:
Association of Arterial Stiffness with Silent Cerebrovascular Lesions: The Ohasama Study.
Cerebrovasc Dis., 31 (4), 329-337 (2011).
DOI: 10.1159/000322599

Masafumi Kikuchi, Nariyasu Mano, Yoshimasa Uehara, Koichi Machida, and Masao Kikuchi:
Cytotoxic and EGFR tyrosine kinase inhibitory activities of aglycone derivatives obtained by enzymatic hydrolysis of oleoside-type secoiridoid glucosides, oleuropein and ligustroside.
J. Nat. Med., 65, 237-240 (2011).
DOI: 10.1007/s11418-010-0476-8

Toshihiro Matsuda, Miki Shimada, Akira Sato, Takanori Akase, Koichi Yoshinari, Kiyoshi Nagata, and Yasushi Yamazoe:
Tumor Necrosis Factor-Alpha-Nuclear Factor-Kappa B-Signaling Enhances St2b2 Expression during 12-O-Tetradecanoylphorbol-13-acetate-Induced Epidermal Hyperplasia.
Biol. Pharm. Bull., 34 (2), 183-190 (2011).

Hiroaki Yamaguchi, Toshiko Takeuchi, Masahiro Okada, Minako Kobayashi, Michiaki Unno, Takaaki Abe, Junichi Goto, Takanori Hishinuma, Miki Shimada, and Nariyasu Mano:
Screening of Antibiotics That Interact with Organic Anion-Transporting Polypeptides 1B1 and 1B3 Using Fluorescent Probes.
Biol. Pharm. Bull., 34 (3), 389-395 (2011).

Nariyasu Mano, Marina Nozawa, Mayumi Sato, Masaru Mori, Hiroaki Yamaguchi, Katsuhiro Kanda, Makoto Nogami, Junichi Goto, Miki Shimada:
Identification and elimination of ion suppression in the quantitative analysis of sirolimus in human blood by LC/ESI-MS/MS.
J. Chromatogr. B, 879, 968-974 (2011).
DOI: 10.1016/j.jchromb.2011.03.011

Nariyasu Mano, Mayumi Sato, Marina Nozawa, Yotaro Matsumoto, Masaru Mori, Hiroaki Yamaguchi, Junichi Goto, and Miki Shimada:
An accurate quantitative LC/ESI-MS/MS method for sirolimus in human whole blood.
J. Chromatogr. B, 879, 987-992 (2011).
DOI: 10.1016/j.jchromb.2011.03.013

Masafumi Kikuchi, Yasunori Yaoita, Nariyasu Mano, Masao Kikuchi:
Structure and cytotoxic activity of enzymatic hydrolysis products of secoiridoid glucosides,
isoligustroside and isooleuropein.
Chem. Biodivers., 8, 651-657 (2011).

Lee R. Hagey, Takashi Iida, Shoujiro Ogawa, Yuuki Adachi, Mizuho Une, Kumiko Mushiake, Masamitsu Maekawa, Miki Shimada, Nariyasu Mano, and Alan F. Hofmann:
Biliary bile acids in birds of the Cotingidae family – (24R,25R)-3α,7α,24-trihydroxy-5β-cholestan-27-oic acid and two epimers (25R and 25S) of 3α,7α-dihydroxy-5β-cholestan-27-oic acid.
Steroids, 76, 1126 -1135 (2011).
DOI: 10.1016/j.steroids.2011.04.017

Taku Obara, Takayoshi Ohkubo, Nariyasu Mano, Nobuo Yaegashi, Shinichi Kuriyama, Yutaka Imai:
Subtypes of Resistant Hypertension Based on Out-of-Office Blood Pressure Measurement.
Hypertension. 58, 4 e28 (2011).
DOI: 10.1161/HYPERTENSIONAHA.111.178996

Tomohiro Hanazawa, Taku Obara, Kei Ogasawara, Takahiro Shinki, Sakiko Katada, Ryusuke Inoue, Hirohito Metoki, Kei Asayama, Masahiro Kikuya, Takayoshi Ohkubo, Nariyasu Mano, and Yutaka Imai:
Low-dose and very low-dose spironolactone in combination therapy for essential hypertension: Evaluation by self-measurement of blood pressure at home.
Clin. Exp. Hypertens, 33, 427-436 (2011).
DOI: 10.3109/10641963.2010.531844

Ayako Furugen, Hiroaki Yamaguchi, Nobuaki Tanaka, Hajime Ito, Kazuaki Miyamori, Asuka Fujikawa, Natsuko Takahashi, Jiro Ogura, Masaki Kobayashi, Takehiro Yamada, Nariyasu Mano, and Ken Iseki:
Quantification of intracellular and extracellular prostanoids stimulated by A23187 by liquid chromatography/electrospray ionization tandem mass spectrometry.
J. Chromatogr. B, 879, 3378-3385 (2011).
DOI: 10.1016/j.jchromb.2011.09.003

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