薬剤部の研究

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業績

 

2020年

Tomonori Sato, Yoshihide Kawasaki, Masamitsu Maekawa, Shinya Takasaki, Kento Morozumi, Masahiko Sato, Shuichi Shimada, Naoki Kawamorita, Shinichi Yamashita, Koji Mitsuzuka, Nariyasu Mano, Akihiro Ito.
Metabolomic analysis to elucidate mechanisms of sunitinib resistance in renal cell carcinoma.
Metabolites, 11(1), 1, (2020).
DOI: 10.3390/metabo11010001

Kazushi Yashima, Taku Obara, Fumiko Matsuzaki, Chihiro Suzuki, Mika Saeki, Mina Koyama, Moeko Hosono, Aoi Noda, Saya Kikuchi, Tetsuro Hoshiai, Shinichi Sato, Masatoshi Saito, Takushi Hanita, Nariyasu Mano.
Evaluation of the safety of taking lamotrigine during lactation period.
Breastfeeding Medicine, in press (2020).

Daisuke Kikuchi, Taku Obara, Misaki Tokunaga, Makoto Shiozawa, Ai Takahashi, Misato Ito, Hiroaki Hino, Ryosuke Miura, Sachiko Hayakawa, Yoshiteru Watanabe.
Drug Prescription for Attention Deficit Hyperactivity Disorder Drugs in Pediatric Outpatients: A Retrospective Survey of Japanese Administrative Data (2012–2018).
Asian Journal of Psychiatry, in press (2020).

Takuma Usuzaki, Shuji Chiba, Minoru Shimoyama, Mami Ishikuro, Taku Obara.
A disparity in the number of studies related to COVID-19 and SARS-CoV-2 between low- and middle-income countries and high-income countries.
International Health, in press (2020).

Aoi Noda, Taku Obara, Michihiro Satoh, Naoto Yagi, Nariyasu Mano, Kenji Kaneko.
Active extraction of experience of adverse drug reactions in children.
The Journal of Pediatric Pharmacology and Therapeutics, in press (2020).

Masami Tsuchiya, Akihisa Esashi, Taku Obara, Ryohkan Funakoshi, Nariyasu Mano.
Implementation of an Adverse Drug Reaction Monitoring System Based on Risk Management Pla.
Journal of Drug Interaction Research, in press (2020).

Junichi Sugawara, Mami Ishikuro, Taku Obara, Tomomi Onuma, Keiko Murakami, Masahiro Kikuya, Fumihiko Ueno, Aoi Noda, Satoshi Mizuno, Tomoko Kobayashi, Yohei Hamanaka, Kichiya Suzuki, Eiichi Kodama, Naho Tsuchiya, Akira Uruno, Yoichi Suzuki, Osamu Tanabe, Hideyasu Kiyomoto, Akito Tsuboi, Atsushi Shimizu, Seizo Koshiba, Naoko Minegishi, Soichi Ogishima, Gen Tamiya, Hirohito Metoki, Atsushi Hozawa, Nobuo Fuse, Kengo Kinoshita, Shigeo Kure, Nobuo Yaegashi, Shinichi Kuriyama, Masayuki Yamamoto.
Maternal Baseline Characteristics and Perinatal Outcomes: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study.
Journal of Epidemiology, Journal of Epidemiology, in press (2020).

Yuki Nakao, Ai Sasaki, Taku Obara, Shinya Abe, Kaori Furusaki, Mari Higaki, Shouko Yoshimachi, Teruaki Gotou.
Knowledge of cervical cancer and human papillomavirus among Japanese women.
Asian Pacific Journal of Cancer Prevention, in press (2020).

Hiroshi Yabuki, Yasushi Matsuda, Tatsuaki Watanabe, Shunsuke Eba, Fumihiko Hoshi, Takashi Hirama, Hisashi Oishi, Tetsu Sado, Masafumi Noda, Akira Sakurada, Masafumi Kikuchi, Hiroaki Yamaguchi, Nariyasu Mano, Yoshinori Okada.
Plasma mycophenolic acid concentration and the clinical outcome after lung transplantation.
Clinical Transplantation, e14088 (2020).
DOI: 10.1111/ctr.14088

Narita A, Nagai M, Mizuno S, Ogishima S, Tamiya G, Ueki M, Sakurai R, Makino S, Obara T, Ishikuro M, Yamanaka C, Matsubara H, Kuniyoshi Y, Murakami K, Ueno F, Noda A, Kobayashi T, Kobayashi M, Usuzaki T, Ohseto H, Hozawa A, Kikuya M, Metoki H, Kure S, Kuriyama S.
Clustering by phenotype and genome-wide association study in autism.
Translational Psychiatry, 10(1), 290 (2020).
DOI: 10.1038/s41398-020-00951-x

Iwama N, Sugiyama T, Metoki H, Saito M, Hoshiai T, Watanabe Z, Tanaka K, Sasaki S, Sakurai K, Ishikuro M, Obara T, Tatsuta N, Nishigori H, Kuriyama SI, Arima T, Nakai K, Yaegashi N; Japan Environment, Children's Study Group.
Associations between Glycosylated Hemoglobin Level at Less Than 24 Weeks of Gestation and Adverse Pregnancy Outcomes in Japan: The Japan Environment and Children's Study (JECS).
Diabetes Research and Clinical Practice, in press (2020).

Usuzaki T, Ishikuro M, Metoki H, Murakami K, Noda A, Ueno F, Kikuya M, Obara T, Kuriyama S.
Comparison among research, home, and office blood pressure measurements for pregnant women: The TMM BirThree Cohort Study.
Journal of Clinical Hypertension, in press (2020).

Murakami K, Ishikuro M, Ueno F, Noda A, Oonuma T, Obara T, Kuriyama S.
Social predictors of continued and indoor smoking among partners of non-smoking pregnant women: the TMM BirThree Cohort Study.
Journal of Epidemiology, in press (2020).

Anna Iwahori, Masamitsu Maekawa, Aya Narita, Akie Kato, Toshihiro Sato, Jiro Ogura, Yu Sato, Masafumi Kikuchi, Atsuko Noguchi, Katsumi Higaki, Torayuki Okuyama, Tsutomu Takahashi, Yoshikatsu Eto, Nariyasu Mano.
Development of a Diagnostic Screening Strategy for Niemann-Pick Diseases Based on Simultaneous Liquid Chromatography-Tandem Mass Spectrometry Analyses of N-Palmitoyl-O-phosphocholine-serine and Sphingosylphosphorylcholine.
Biological and Pharmaceutical Bulletin, 43(9), 1398-1406 (2020).
DOI: 10.1248/bpb.b20-00400

Yonezawa Y, Obara T, Yamashita T, Sugawara J, Ishikuro M, Murakami K, Noda A, Ueno F, Suzuki S, Suganuma H, Kuriyama S.
Fruit and vegetable consumption before and during pregnancy and birth weight of new-borns in Japan: the Tohoku medical megabank project birth and three-generation cohort study.
Nutrition Journal, in press (2020).

Wagata M, Ishikuro M, Obara T, Nagai M, Mizuno S, Nakaya N, Nakamura T, Hirata T, Tsuchiya N, Metoki H, Ogishima S, Hozawa A, Kinoshita K, Kure S, Yaegashi N,
Yamamoto M, Kuriyama S, Sugawara J.
Low Birth Weight and Abnormal Pre-pregnancy Body Mass Index Were at Higher Risk for Hypertensive Disorders of Pregnancy.
Pregnancy Hypertension, in press (2020).

Aoi Noda, Takamasa Sakai, Masami Tsuchiya, Gen Oyanagi, Taku Obara, Nariyasu Mano.
Characteristics of Adverse Events Following Immunization Reporting in Children: The Japanese Adverse Drug Event Report Database.
Vaccines, in press (2020).

Tomofumi Ishikawa, Taku Obara, Kazutaka Jin, Hidekazu Nishigori, Keiko Miyakoda, Manabu Akazawa, Nobukazu Nakasato, Nobuo Yaegashi, Shinichi Kuriyama, Nariyasu Mano.
Folic acid prescribed to prenatal and postpartum women who are also prescribed antiepileptic drugs in Japan: Data from a health administrative database.
Birth Defects Research, in press (2020).

Shinya Takasaki, Hisanobu Adachi, Yoshihide Kawasaki, Masafumi Kikuchi, Akihiro Ito, Nariyasu Mano.
Importance of therapeutic drug monitoring to detect drug interaction between pazopanib and warfarin: a case report.
Journal of Pharmacy & Pharmaceutical Sciences, 23, 200-205 (2020).
DOI: 10.18433/jpps30868

Tomotaka Ueno, Naoki Tanaka, Hirofumi Imoto, Masamitsu Maekawa, Atsushi Kohyama, Kazuhiro Watanabe, Fuyuhiko Motoi, Takashi Kamei, Michiaki Unno, Takeshi Naitoh.
Mechanism of Bile Acid Reabsorption in the Biliopancreatic Limb After Duodenal-Jejunal Bypass in Rats.
Obesity Surgery, 30(7), 2528-2537 (2020).
DOI: 10.1007/s11695-020-04506-3

Anna Iwahori, Masamitsu Maekawa, Yoshitomi Kanemitsu, Yotaro Matsumoto, Yoshihisa Tomioka, Aya Narita, Torayuki Okuyama, Yoshikatsu Eto, Daisuke Saigusa, Nariyasu Mano.
Global metabolomics analysis of serum from patients with Niemann Pick disease type C.
Medical Mass Spectrometry, 4(1), 6 (2020).
DOI: 10.24508/mms.2020.06.006

Kei Higuchi, Toshihiro Sato, Yangzom D Bhutia, Vadivel Ganapathy.
Involvement of a Na+-coupled Oligopeptide Transport System for β-Amyloid Peptide (Aβ 1-42) in Brain Cells.
Pharmaceutical Research, 37(6), 98 (2020).
DOI: 10.1007/s11095-020-02835-7

Jonathan Kopel, Kei Higuchi, Bojana Ristic, Toshihiro Sato, Sabarish Ramachandran, Vadivel Ganapathy.
The Hepatic Plasma Membrane Citrate Transporter NaCT (SLC13A5) as a Molecular Target for Metformin.
Scientific Reports, 10(1), 8536 (2020).
DOI: 10.1038/s41598-020-65621-w

Takuma Usuzaki, Mami Ishikuro, Keiko Murakami, Aoi Noda, Fumihiko Ueno, Taku Obara, Shinichi Kuriyama.
How can we evaluate whether an association is truly inter-generational?.
Journal of Hypertension, 38(7), in press (2020).

Aoi Noda, Takamasa Sakai, Taku Obara, Makoto Miyazaki, Masami Tsuchiya, Gen Oyanagi, Yuriko Murai, Nariyasu Mano.
Characteristics of Pediatric Adverse Drug Reaction Reports in the Japanese Adverse Drug Event Report Database.
BMC Pharmacology and Toxicology, in press (2020).

Ishii Hideaki, Obara Taku, Kusano, Kanichi, Kijima-Suda Isao.
Quantitative analysis of paracetamol, metacetamol, and orthocetamol in equine urine from racehorses in Japan using liquid chromatography–electrospray ionisation–tandem mass spectrometry.
Drug Testing and Analysis, in press (2020).

Kensuke Shigeta, Masafumi Kikuchi, Masaki Tanaka, Shinya Takasaki, Hisashi Oishi, Tetsu Sado, Yasushi Matsuda, Masafumi Noda, Yoshinori Okada, Nariyasu Mano, Hiroaki Yamaguchi.
Development of a precise quantitative method for monitoring sirolimus in whole blood using LC/ESI-MS/MS.
Biomedical Chromatography, e4853 (2020).
DOI: 10.1002/bmc.4853

Yangzom D.Bhutia, JiroOgura, Paul J. Grippo, Carolina Torres, Toshihiro Sato, Mitchell Wachtel, Sabarish Ramachandran, Ellappan Babu, Sathish Sivaprakasam, Devaraja Rajasekaran, Bradley Schniers, Nhu On, Logan Smoot, Muthusamy Thangaraju, Jaya P. Gnana-Prakasam, Vadivel Ganapathy. Chronic exposure to excess iron promotes EMT and cancer via p53 loss in pancreatic cancer.
Asian Journal of Pharmaceutical Sciences, 15(2), 237-251 (2020).
DOI: 10.1016/j.ajps.2020.02.003

Hideaki Ishii, Taku Obara, Isao Kijima-Suda.
Investigation of plasma concentrations of paracetamol, metacetamol, and orthocetamol in Japanese race horses using liquid chromatography-electrospray ionisation-tandem mass spectrometry.
Drug Testing and Analysis, in press (2020).


Mari S. Oba, Yoshitaka Murakami, Michihiro Satoh, Takahisa Murakami, Mami Ishikuro, Taku Obara, Kazuhiko Hoshi, Yutaka Imai, Takayoshi Ohkubo, Hirohito Metoki.
Period-specific effects of lower gestational weight gain on birthweight using causal diagram: The babies' and their parents' longitudinal observation in Suzuki Memorial Hospital on intrauterine period (BOSHI) study.
Journal of Developmental Origins of Health and Disease, in press (2020).

Tsuchiya M, Obara T, Miyazaki M, Takamura C, Mano N.
The quality assessment of the Japanese Adverse Drug Event Report database using vigiGrade.
International Journal of Clinical Pharmacy. in press (2020).
DOI: 10.1007/s11096-020-00969-7

Ishikawa T, Obara T, Kikuchi S, Kobayashi N, Miyakoda K, Nishigori H, Tomita H, Akazawa M, Yaegashi N, Kuriyama S, Mano N.
Antidepressant prescriptions for prenatal and postpartum women in Japan: A health administrative database study.
Journal of Affective Disorders. 264, 295-303 (2020).
DOI: 10.1016/j.jad.2020.01.016

Hozawa A, Tanno K, Nakaya N, Nakamura T, Tsuchiya N, Hirata T, Narita A, Kogure M, Nochioka K, Sasaki R, Takanashi N, Otsuka K, Sakata K, Kuriyama S, Kikuya M, Tanabe O, Sugawara J, Suzuki K, Suzuki Y, Kodama EN, Fuse N, Kiyomoto H, Tomita H, Uruno A, Hamanaka Y, Metoki H, Ishikuro M, Obara T, Kobayashi T, Kitatani K, Takai-Igarashi T, Ogishima S, Satoh M, Ohmomo H, Tsuboi A, Egawa S, Ishii T, Ito K, Ito S, Taki Y, Minegishi N, Ishii N, Nagasaki M, Igarashi K, Koshiba S, Shimizu R, Tamiya G, Nakayama K, Motohashi H, Yasuda J, Shimizu A, Hachiya T, Shiwa Y, Tominaga T, Tanaka H, Oyama K, Tanaka R, Kawame H, Fukushima A, Ishigaki Y, Tokutomi T, Osumi N, Kobayashi T, Nagami F, Hashizume H, Arai T, Kawaguchi Y, Higuchi S, Sakaida M, Endo R, Nishizuka S, Tsuji I, Hitomi J, Nakamura M, Ogasawara K, Yaegashi N, Kinoshita K, Kure S, Sakai A, Kobayashi S, Sobue K, Sasaki M, Yamamoto M.
Study profile of The Tohoku Medical Megabank Community-Based Cohort Study.
Journal of Epidemiology, in press (2020).

Daisuke Kikuchi, Taku Obara, Takuma Usuzaki, Yudai Yonezawa, Takahiro Yamashita,
Gen Oyanagi, Aoi Noda, Fumihiko Ueno, Keiko Murakami, Hiroko Matsubara, Mami Ishikuro, Hirohito Metoki, Masahiro Kikuya, Shinichi Kuriyama.
Evaluating folic acid supplementation among Japanese pregnant women with dietary intake of folic acid lower than 480 µg per day: results from TMM BirThree Cohort Study.
The Journal of Maternal-Fetal & Neonatal Medicine, in press (2020).

Masami Tsuchiya, Taku Obara, Makoto Miyazaki, Aoi Noda, Chizuko Takamura, Nariyasu Mano.
The quality assessment of Japanese Adverse Drug Event Report database (JADER) using vigiGrade.
International Journal of Clinical Pharmacy, in press (2020).

Tomofumi Ishikawa, Taku Obarab, Saya Kikuchi, Natsuko Kobayashi, Keiko Miyakoda,
Hidekazu Nishigori, Hiroaki Tomita, Manabu Akazawa, Nobuo Yaegashi, Shinichi Kuriyama, Nariyasu Mano.
Antidepressant prescriptions for prenatal and postpartum women in Japan: A health administrative database study.
Journal of Affective Disorders, in press (2020).

Noriyuki Iwama, Mari S. Oba, Michihiro Satoh, Takayoshi Ohkubo, Mami Ishikuro, Taku Obara, Satomi Sasaki, Masatoshi Saito, Yoshitaka Murakami, Shinichi Kuriyama Nobuo Yaegashi, Kazuhiko Hoshi, Yutaka Imai, Hirohito Metoki, and The BOSHI Study Group.
Association of maternal home blood pressure trajectory during pregnancy with infant birth weight: The BOSHI study.
Hypertension Research, in press (2020).

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