薬剤部の研究

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業績

 

2009年

Lee R. Hagey, Genta Kakiyama, Akina Muto, Takashi Iida, Kumiko Mushiake, Takaaki Goto, Nariyasu Mano, Junichi Goto, Cleida A. Oliveria and Alan F. Hofmann:
A new, major C27 biliary bile acid in the red-winged tinamou (Rhynchotus rufescens): (25R)-1β,3α,7α-trihydroxy-5β-cholestan-27-oic acid.
J. Lipid Res., 50, 651-657 (2009).
DOI: 10.1194/jlr.M800521-JLR200

Eiichi Yamamoto, Takashi Kato, Nariyasu Mano and Naoki Asakawa:
Effective on-line extraction of drugs from plasma using a restricted-access media column in column-switching HPLC equipped with a dilution system: application to the simultaneous determination of ER-118585 and its metabolites in canine plasma.
J.Pharm. Biomed. Anal., 49, 1250-1255 (2009).
DOI: 10.1016/j.jpba.2009.02.022

Genta Kakiyama, Akina Muto, Miki Shimada, Nariyasu Mano, Junichi Goto, Alan F. Hofmann and Takashi Iida:
Chemical synthesis of 3β-sulfooxy-7β-hydroxy-24-nor-5-cholenoic acid: An internal standard for mass spectrometric analysis of the abnormal Δ5-bile acids occurring in Niemann-Pick disease.
Steroids, 74, 766-772 (2009).
DOI: 10.1016/j.steroids.2009.04.007

Kie Ito, Taku Obara, Takayoshi Ohkubo, Kenta Gonokami, Takahiro Shinki, Taku Shibamiya, Manami Nakashita, Mitsuru Kobayashi, Jin Funahashi, Azusa Hara, Hirohito Metoki, Kei Asayama, Ryusuke Inoue, Masahiro Kikuya, Nariyasu Mano, Yutaka Imai, and J-HOME Study Group:
Influence of home blood pressure measuring conditions in the evening on the morning-evening home blood pressure difference in treated hypertensive patients: the J-HOME study.
Blood Pressure Monitoring, 14, 160-165 (2009).
DOI: 10.1097/MBP.0b013e32832e2a40

Masato Ohbuchi, Masaaki Miyata, Daichi Nagai, Miki Shimada, Kouichi Yoshinari, and Yasushi Yamazoe:
Role of enzymatic N-hydroxylation and reduction in flutamide metabolite-induced liver toxity.
Drug Metab. Dispos., 37, 97-105 (2009).

Nariyasu Mano, Sayaka Aoki, Takuma Yamazaki, Yoko Nagaya, Masaru Mori, Kohei Abe, Miki Shimada, Hiroaki Yamaguchi, Takaaki Goto and Junichi Goto:
Analysis of phosphorylated peptides by double pseudo-neutral loss extraction coupled with derivatization using N-(4-bromobenzoyl)aminoethanethiol.
Anal. Chem., 81, 9395-9401 (2009).
DOI: 10.1021/ac9017988

Taku Obara, Kie Ito, Takayoshi Ohkubo, Taku Shibamiya, Takahiro Shinki, Manami Nakashita, Azusa Hara, Hirohito Metoki, Ryusuke Inoue, Kei Asayama, Masahiro Kikuya, Nariyasu Mano, Yutaka Imai and the J-HOME Study Group:
Uncontrolled hypertension based on morning and evening home blood pressure measurements from the J-HOME Study.
Hypertens. Res., 32, 1072-1078 (2009).
DOI: 10.1038/hr.2009.152

Nomoto Masahiro, Masaaki Miyata, Shanai Yin, Yasushi Kurata, Miki Shimada, Kouichi Yoshinari, Frank J Gonzalez, Kokichi Suzuki, Shigeki Shibasaki, Tohru Kurosawa, and Yasushi Yamazoe:
Bile acid-induced elevated oxidative stress in the absence of farnesoid X receptor.
Biol. Pharm. Bull., 32, 172-178 (2009).

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